These settings are best for the plug and play devices. Incorrect Audio Settings: Default audio settings are best if you don’t want to face any issues. There are a few quick solutions but first, learn what the issues really are. All these reasons can mute your windows 10 after unplugging the headphone. There can be various reasons for this issue, like incorrect audio settings, outdated sound drivers, unsupported speakers, and registry or hardware issues. 10 Conclusion How To Fix No Sound After Unplugging Headphones In Windows 10?